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Hepatitis B

Monday, 04 December 2023



Customer question:

What is hepatitis B? Anonymous customer's question



Pharmacist's answer:

Hepatitis B is a viral liver infection caused by the hepatitis B virus (HBV). This virus is highly contagious and is transmitted through blood, body fluids, and other bodily secretions. Hepatitis B infection can have different clinical courses, from mild cases that are automatically controlled by the immune system to more severe cases that can lead to chronic inflammation of the liver, cirrhosis, or liver cancer.

Critical features of hepatitis B include:

  • Transmission of the virus: Hepatitis B virus is transmitted through blood and other body fluids such as semen, vaginal fluids, saliva, and breast milk. It can also be transmitted during childbirth from an infected mother to a newborn.
  • Symptoms: Hepatitis B symptoms can vary, including fatigue, abdominal pain, loss of appetite, nausea, jaundice (yellowing of the skin and whites of the eyes), dark urine, and light-colored stools. In some cases, the infection can occur without symptoms.
  • Chronic infection: in some people, especially newborns and children who are infected with hepatitis B, the infection develops into a chronic form. Chronic infection means the virus remains in the body, leading to long-term liver inflammation.
  • Cirrhosis and liver cancer: Long-term chronic hepatitis B infection can lead to severe complications such as cirrhosis of the liver and liver cancer.
  • Vaccination Prevention: Vaccination is an effective way to prevent hepatitis B infection. Vaccination is widely available and is part of routine vaccinations in many countries.

Because of the potentially severe consequences associated with hepatitis B, it is essential to recognize the infection, treat it in time, and implement preventive measures. Vaccination is a vital part of these preventive measures.



Can hepatitis B be deadly?

Yes, hepatitis B can lead to fatal complications in some cases, especially if the infection becomes chronic and leads to severe liver damage, such as cirrhosis or liver cancer. It is essential to understand that most people who contract hepatitis B automatically clear the infection and make a full recovery. However, in some people, the infection becomes chronic, increasing the risk of severe health problems.

Significant complications that can arise from chronic hepatitis B infection include:

  • Cirrhosis of the liver: Cirrhosis is advanced scarring, which can limit liver function. This condition is severe and can lead to many complications, including an increased risk of bleeding and liver failure.
  • Liver cancer: long-term chronic hepatitis B infection increases the risk of developing liver cancer.
  • Liver failure: in the advanced stages of cirrhosis, liver failure can occur, which is a life-threatening condition.

In newborns and young children, the risk of chronic hepatitis B infection is higher, but adults are also at risk. Treatment and monitoring of hepatitis B infection is crucial to prevent serious complications. Vaccination remains the most effective way to prevent hepatitis B infection and reduce the risk of its complications. Regular vaccination is recommended, especially for children, healthcare workers, and other groups at higher risk of infection.



What causes hepatitis B?

Hepatitis B is caused by the hepatitis B virus (HBV), part of the Hepadnaviridae family. The virus is highly contagious and transmitted through an infected person's blood and other bodily fluids. The key ways hepatitis B virus is transmitted include:

  • Blood transmission: infection can be transmitted through blood, for example, by sharing contaminated needles during drug use, blood transfusions, sharing syringes during medical procedures, or using infected tattooing and piercing tools.
  • Sexual contact: the virus can be transmitted through unprotected sexual contact with an infected person. Hepatitis B infection is one of the sexually transmitted diseases.
  • From mother to child: the infection can be passed from mother to child during or after childbirth through contact with infected blood or other body fluids.
  • Sharing personal items: sharing personal items such as razors or toothbrushes can increase the risk of virus transmission

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  • Medical procedures: in some cases, the virus is transmitted during medical procedures, especially when proper infection prevention protocols are not followed.
  • Occupational infection: Healthcare workers and others exposed to blood contamination may be at risk of occupational infection.

It is important to emphasize that the hepatitis B virus is not transmitted through contact, such as hugging, shaking hands, coughing, or sneezing. Vaccination is an effective way to prevent hepatitis B infection, especially if given in childhood or when exposed to an increased risk of infection.



Which type of hepatitis is the most common?

The frequency of individual types of hepatitis can vary by geographic area, demographic characteristics, and other factors. On a global scale, hepatitis B and hepatitis C are among the most common types of hepatitis.

  • Hepatitis B (HBV): Hepatitis B is globally widespread and is one of the most common types of hepatitis. The hepatitis B virus is transmitted through blood, body fluids, and other bodily secretions. Vaccination is an effective way to prevent hepatitis B infection, and although HBV infection numbers are declining due to widespread vaccination, it remains a significant public health challenge.
  • Hepatitis C (HCV): Hepatitis C is another widespread global problem. Hepatitis C virus is transmitted primarily through blood, through sharing of infected needles during drug use, blood transfusions, medical procedures involving blood contamination, and other routes of blood exposure. The development of effective drugs known as direct antiviral agents (DAAs) has led to significant advances in treating hepatitis C.
  • Hepatitis A (HAV): Hepatitis A is usually less severe than hepatitis B and C. Hepatitis A infection is spread through contaminated food and water and close contact with an infected person. Vaccination is available to prevent hepatitis A infection.

In addition, there are other types of hepatitis, such as hepatitis D and E, which are not as widespread and have specific modes of transmission. It is essential to be aware of the risks of contracting hepatitis, get tested if you are at risk, and get vaccinated when appropriate.



Who is most susceptible to hepatitis B infection?

Hepatitis B (HBV) infection can occur in people of all ages and from different groups, but certain groups are more at risk of infection. Here are some groups that may be more susceptible to infection:

  • Newborns and children: children born to mothers with hepatitis B are at risk of infection during delivery. Therefore, newborns are usually given the first hepatitis B vaccine in combination with immunoglobulin.
  • People living with an HBV-positive person: Those who share a household with an infected person have an increased risk of infection because they are exposed to the body fluids of an infected person.
  • Persons who have sexual relations with an infected partner: unprotected sexual contact with an infected person increases the risk of transmission of the hepatitis B virus.
  • People who share needles: drug users who share hypodermic needles or other injecting equipment are at risk of transmitting the virus.
  • Healthcare workers: workers who come into contact with blood or other body fluids during work have an increased risk of infection.
  • People traveling to areas with a high prevalence of hepatitis B: in some parts of the world, hepatitis B is more prevalent, so travelers visiting these areas may be at risk of infection.
  • Homosexual men: a group of men who have sex with other men may have an increased risk of hepatitis B infection.
  • People with HIV infection: People who are infected with HIV may be more susceptible to hepatitis B infection.

Vaccination against hepatitis B is an effective preventive method and is recommended for all newborns and persons from exposed risk groups. Vaccination is an important measure to reduce the incidence of hepatitis B and prevent serious complications.



How often should we be vaccinated against hepatitis B?

The number of hepatitis B vaccine doses and the vaccination schedule may vary by age, health status, and other factors. The standard hepatitis B vaccination includes a series of doses that stimulate the immune system to develop protective antibodies against the hepatitis B virus. The first dose of the vaccine is usually given at birth or in early childhood. The second dose follows a few weeks after the first dose. The third dose is usually given a few months after the second dose.

After completing the entire series of doses, a person is vaccinated against hepatitis B and has established protection against infection. In addition, accelerated vaccination schedules are also available for adults or those who require rapid protection. In such cases, vaccines can be given on an accelerated schedule, but completing the prescribed series of doses is essential.

If someone has missed one dose or has not completed the entire series, continuing with the remaining doses is recommended to achieve complete protection. Consult your doctor or other health care professional for specific guidelines regarding hepatitis B vaccination. Guidelines may vary based on local health policies and practices.



Interesting reading: Hepatitis C

Interesting reading: Hepatitis B vaccination



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