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Monday, 09 October 2023



Customer question:

Where is the sciatic nerve located? Anonymous customer's question



Pharmacist's answer:

The sciatic nerves branch from the lower back through the hips and buttocks and down each leg. The sciatic nerve is the longest and widest nerve in the human body. The primary role of the sciatic nerve is to innervate the muscles in the thigh and leg and to provide sensory information from this area back to the brain. It is important to note that sciatica pain can often follow the path of this nerve, originating mainly in the lower back or buttocks and traveling down the back of the thigh and can spread to the lower leg and foot.



What is the role of the sciatic nerve?

Motor functions:

The sciatic nerve innervates or supplies several muscles, allowing them to contract and perform movements. Specifically, it innervates the thigh muscles, which are responsible for bending the knee and extending the hip. Through its two main branches (the tibial nerve and the common peroneal/fibular nerve), it also innervates the muscles that control the movement of the foot and toes.

This includes plantar flexion (pointing the toes), dorsiflexion (lifting the foot) and other complex movements of the foot and toes.

Sensory functions:

The sciatic nerve carries sensory information from the skin and tissues back to the brain. This includes sensations such as touch, temperature, pain and proprioception (the sense of the relative position of one's own body parts). It captures the feeling of the skin on the back of the thigh. Through its branches, it also provides sensation to most of the lower leg and foot, except for a small area on the inside of the metatarsal and arch of the foot that is covered by another nerve.



Who most often has problems with sciatica?

Men have been shown to experience sciatica up to three times more often than women. And while people can suffer from sciatic nerve pain as early as their 20s, it is most common in adults in their 40s and 50s.



Can we get sciatica during pregnancy?

Yes, sciatica can also occur during pregnancy and is a relatively common problem. While the symptoms of sciatica during pregnancy may be similar to those experienced outside of pregnancy (such as sharp pain, tingling, or numbness that spreads down the back or side of the leg), treatment strategies may differ. It is imperative that pregnant women consult a doctor before taking any medication or undergoing treatment.

Reasons for sciatica during pregnancy include:

  • Weight gain and changes in body posture: Pregnancy often causes weight gain and shifts in the center of gravity due to the growing baby. This can cause postural changes that can put extra pressure on the sciatic nerve.
  • Uterine pressure on the sciatic nerve: As the fetus and uterus grow, they can put pressure on the sciatic nerve, especially in the later stages of pregnancy.
  • Hormonal changes: during pregnancy, the body produces an increased amount of the hormone relaxin, which helps relax the uterus and also loosens ligaments in the pelvis. This increased joint laxity can cause changes in the structure of the pelvis, which can put pressure on the sciatic nerve.
  • Water retention and swelling: Some pregnant women experience swelling or edema, which can compress nerve pathways.
  • Muscle spasms: increased load and stress on the back muscles can cause them to spasm, which can cause compression of the sciatic nerve.
  • Piriformis syndrome: The piriformis muscle, located in the buttock area, can contract or tighten due to pregnancy-related changes, which can compress the sciatic nerve as it runs under (or in some people through) the muscle.



Interesting reading: How long does sciatica last?

Interesting reading: Diet for sciatica



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