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Thursday, 09 November 2023



Customer question:

Is the last stage of liver cancer curable? Anonymous customer's question



Pharmacist's answer:

The curability of late-stage liver cancer, also known as advanced or end-stage liver cancer, depends on a variety of factors and can be challenging. Advanced liver cancer usually refers to stage IV liver cancer, where the cancer has already spread to other parts of the body, making it more difficult to treat.

Several factors influence the prognosis and the possibility of curing advanced liver cancer:

  • Extent of spread: the number and location of distant metastases (the spread of cancer to other organs) play an important role. Widespread metastases often reduce the success of treatment.
  • General health: the patient's general health is important, including his ability to tolerate treatment and surgery. Patients in good general health often have more treatment options.
  • Liver function: the health of the remaining liver tissue and the patient's liver function are critical. In some cases, a liver transplant is considered if the tumor can be completely removed and the patient meets specific criteria.
  • Tumor characteristics: the size, number and characteristics of liver tumors and the presence of vascular invasion affect the treatment approach and prognosis.

Treatment options for advanced liver cancer may include:

  • Palliative care: in cases where a cure is not possible, the focus may be on palliative care, which aims to provide relief of symptoms and improve the patient's quality of life.
  • Systemic therapies: these treatments include chemotherapy, targeted therapies, and immunotherapy, which can help slow cancer progression, control symptoms, and potentially prolong survival.
  • Radiation therapy: Radiation therapy may be used to relieve pain, control bleeding, or treat specific tumors.
  • Liver-targeted therapies: Procedures such as transarterial chemoembolization (TACE), radioembolization (yttrium-90), or ablation can be considered to directly target liver tumors.
  • Liver transplant: in some carefully selected cases, a liver transplant may be an option if the cancer is confined to the liver and the patient meets specific criteria. However, transplantation is usually not possible in advanced stage liver cancer with extensive metastases.

The prognosis for advanced liver cancer is generally less favorable than for cancer detected at an earlier stage. It is critical for individuals with advanced liver cancer to work closely with their healthcare team to explore the best treatment options and receive comprehensive supportive care. Each patient's situation is unique and treatment decisions must be based on a careful assessment of the specific circumstances and the patient's wishes.



Interesting reading: Liver cancer

Interesting reading: Liver-failure signs



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